The Orexin Hypocretin System: Physiology and Pathophysiology (Contemporary Clinical Neuroscience)
Seiji Nishino, Takeshi Sakurai
This cutting-edge review of the orexin/hypocretin system sets the stage for advanced research on the pathological mechanisms underlying the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation. Topics of interest include assessment of functions and the physiology of orexin/hypocretin, its pathophysiology in human narcolepsy-cataplexy, and possible treatments and pharmacology. The authors also introduce several experimental methods for orexin/hypocretin research, and, using multidisciplinary approaches, explain their uses and limitations.
Категорії:
Рік:
2005
Видання:
1
Видавництво:
Humana Press
Мова:
english
Сторінки:
416
ISBN 10:
1592599508
ISBN 13:
9781592599509
Файл:
PDF, 4.00 MB
IPFS:
,
english, 2005
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